Weifang 3V Bioengineering Group Co., Ltd.

Measurement of Rheumatoid factor (RF) concentration in human serum. RF are a heterogeneous group of autoantibodies directed against the antigenic determinants on the Fc-region of Ig G molecules. Denatured IgG is the target antibody for autoantibodies of RF. Few normal and part of the elderly can be positive, mainly seen in rheumatoid arthritis, but other diseases can also be seen in patients with rheumatoid arthritis, RF emerge more higher titers, suggesting accompanied by severe joint dysfunction, the prognosis is poor.

【Test Principle】

Latex- enhanced immunoturbidimetric two point end assay. RF in serum and specific antibody will reaction and generate a cloudy particles, It is dispersed in medium, using turbidimetric method to measure turbidity at 660 nm, with the presence of a certain amount of antibody, turbidity is proportional to the RF concentration.